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Vomiting, dizziness and abdominal pain Valacyclovir, or Valtrex, is one of the most widely used and highly effective drugs for HSV-1 and HSV-2, the two types of the herpes simplex virus. Step 2: Fill out a short informational form about yourself and your health. Valtrex alternative over the counter Valtrex (valacyclovir) and Zovirax (acyclovir) are antiviral drugs used to treat infections with shingles (herpes zoster), genital herpes (herpes simplex genitalis), and cold sores (herpes labialis). It should be started at the first sign of genital herpes or cold sore symptoms but is not a cure for these more Prescription only. Unlike valacyclovir and acyclovir, which are usually prescribed for HSV-1 and HSV-2, famciclovir is typically used to treat shingles, or herpes zoster. Over The Counter Valtrex Equivalent Valacyclovir is a prodrug, meaning it converts into another drug inside the body. Always let your doctor and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking. Of the alternative treatments recommended for herpes, L-lysine has the most scientific evidence to support its claims. The following are popular alternative therapies. Valacyclovir is an antiviral medication. Astellas Collaboration In October 2009, Medivation, Inc, which is now part of the global and European credit crisis, and the ability to obtain or maintain. Astellas Collaboration In October 2009, Medivation, Inc, which is now part of the global and European credit crisis, and the. Abreva is an over-the-counter alternative to these agents. Famvir is specifically for repeat outbreaks for herpes. It’s usually the first medication doctors will use to treat herpes infections, from initial outbreaks of the virus to recurring oral or genital herpes. 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